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The first nutritional study of experimental atherosclerosis was by Ignatowski in 1908. Feeding meat to adult rabbits and milk and egg yolk to weanling rabbits caused atherosclerosis. The discovery in 1912 that dietary cholesterol was atherogenic turned attention to fat and cholesterol. In 1926, Clarkson and Newburgh found the amount of cholesterol in animal protein was insufficient to be atherogenic. In 1940, Meeker and Kesten demonstrated that casein was more atherogenic than soy24.
IgA antibodies to milk antigens are associated with severe atherosclerosis. A study of 23 subjects with angiographically assessed atherosclerotic lesions and 20 healthy control subjects showed significant correlations of anti-apoprotein and antilipoprotein IgA with antimilk protein IgA and total IgA25.
Chinese herbal medicines can provide multiple benefits in the treatment and prevention of cardiovascular disease with minimal toxicity, lowering cholesterol, triglycerides, LDL, blood pressure, blood sugar, and increasing coronary and cerebral arterial circulation. Protective effects on liver and kidney functions, anticoagulant effects, and improved immune function further reduce the impact of pre-existing disease in hypertensive and diabetic patients. The tables below indicate the complex pharmacological effects of commonly used herbs for hyperlipidemia, atherosclerosis, and their causative factors.
Antibacterial/Cholesterol reduce
Astragalus (Huang Qi)
Crataegus (Shan Zha)
Lycium bark (Di Gu Pi)
Polygonum multiflorum (He Shou Wu)
Salvia (Dan Shen)
Cholesterol reduce/LDL reduce
Angelica sinensis (Dang Gui)
Astragalus (Huang Qi)
Ganoderma (Ling Zhi)
Salvia (Dan Shen)
Tribulus (Bai Ji Li)
Cholesterol reduce/Liver protective
Angelica sinensis (Dang Gui)
Astragalus (Huang Qi)
Ganoderma (Ling Zhi)
Gynostemma (Jiao Gu Lan)
Lycium fruit (Gou Qi Zi)
Polygonum cuspidatum (Hu Zhang)
Dairy products and high sugar intake increase bacterial and fungal overgrowth in the intestines and contribute to elevated cholesterol and triglycerides. A zero dairy, low sugar diet that includes whole grains, fruits, vegetables, garlic and ginger, combined with herbal medicines possessing antibacterial and cholesterol lowering effects, treats both the root and branch of the disorder26,27,28,29,30,31. We can describe this process from a TCM perspective as damp heat in the bowels (intestinal dysbiosis) transmitting toxins to the Liver, generating phlegm and blood stasis (atheroma and plaque) in the jing mai and luo vessels (major and minor arteries, veins, and capillaries). Additional antibacterial, antifungal, and antispasmodic herbs for digestive complaints of gas, bloating, constipation, and diarrhea, such as Aucklandia (Mu Xiang), Cardamon (Sha Ren), Moutan (Mu Dan Pi), Perilla leaf (Zi Su Ye), and Elsholtzia (Xiang Ru), may be added to the above herbs to optimize the clinical response.
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