Pituitary macroadenoma

Greetings. I have a patient with an active pituitary macro adenoma to whom I am treating with acupuncture among other alternative therapies. Almost all symptoms have disappear with the exception of a refractory headache which main quality is a stabbing quality and fluctuating in location, sometimes is occipital other is temporal. It is also associated to great anxiety and pain in the left pectoral. Any advice in treatment?